Clinician Investigator, T32 Research Fellow NCSU CVM Department of Population Health and Pathobiology Raleigh, North Carolina, United States
Disclosure(s):
John A. Shamoun, DVM: No financial relationships to disclose
Presentation Description / Summary: Uropathogenic E. coli account for the vast majority of UTI cases in dogs. These bacteria harness different genetic tools to aid in colonization of the urinary tract, including strategies of antimicrobial resistance and resilience. An example of resilience includes the formation of bacterial biofilm to aid in immune evasion. We will discuss the topic of bacterial biofilm in the setting of UPEC UTI including pathogenesis, genetic determinants, and investigation of its role in the clinical setting.
Learner Outcomes: 1. Understand the pathogenesis of UPEC biofilm formation and why its formation is favorable to UPEC in the setting of UTI. 2. Understand how researchers have approached investigation of this virulence strategy to aid in management of UPEC cases in the clinical setting.
Learning Objectives:
1. Understand the pathogenesis of UPEC biofilm formation and why its formation is favorable to UPEC in the setting of UTI.
2. Understand how researchers have approached investigation of this virulence strategy to aid in management of UPEC cases in the clinical setting.