Graduanda de Medicina Veterinária Faculdade de Medicina Veterinária e Zootecnia - Universidade de São Paulo São Paulo, Sao Paulo, Brazil
Abstract:
Background: Acid-base and electrolyte disorders may occur in dogs with acute kidney injury due to leptospirosis.
Objective: To evaluate the occurrence of acid-base and electrolyte disorders in dogs with leptospirosis. Animals: Data from 18 dogs with leptospirosis treated at the Veterinary Teaching Hospital of the University of Sao Paulo.
Methods: Venous blood gas analysis was used to evaluate the acid-base status. Serum concentrations of total calcium (Ca), total magnesium (Mg), and phosphorus (P) were also assessed. Data are presented as mean +/- SD (min – max).
Results: Serum levels of Ca, Mg and P were 8.98 ±1.49 mg/dL (6.69-10.73), 2.9 ± 0.93 mg/dL (2.22-4.2) and 21.25 ±4.67 mg/dL (3.0-24.05), respectively. The occurrence of hypocalcemia and hyperphosphatemia was found in 50% of the cases; 33.3% of dogs had hypermagnesemia. Acid-base disturbances were observed in 33.3% of dogs, with 50% presenting metabolic acidosis and 50% mixed disturbances. The mortality rate was higher than 80% in dogs with acid-base disturbances.
Conclusions: The assessment of acid-base status and electrolyte profile should be recommended in dogs with leptospirosis.
